Physical Pharmaceutics - I (Practical Book)

It is indeed a matter of great pride that, the Pharmacy Council of India (PCI), New Delhi has framed Bachelor of Pharmacy (B. Pharm.) course regulations 2014. The Physical Pharmaceutics-I is a very important subject at Second year of the course of B. Pharm. programme. It is a great pleasure to present this book in the hands of readers. The book is strictly written as per syllabus framed by PCI under Section 6, 7 and 8 of Regulation 2014. I have made an attempt to make this subject and the concepts of the experiment more simple and understandable to the budding pharmacy student readers. The sequence of experiments given in syllabus is maintained while writing the script. In this book wherever needed full forms and abbreviations, pictorial diagrams, tabular data, examples of formulation including marketed products and manufacturers are given. Model questions generally asked during synopsis and viva-voce examinations are given at the end of every experiment to exercise on experiment performed.

1. Determination the solubility of drug at room temperature

2. Determination of pKa value by Half Neutralization/Henderson Hasselbalch equation.

3. Determination of Partition co-efficient of benzoic acid in benzene and water.

4. Determination of Partition co-efficient of Iodine in CCl4 and water.

5. Determination of % composition of NaCl in a solution using phenolwater system by CST method.

6. Determination of surface tension of given liquids by drop count and drop weight method.

7. Determination of HLB number of a surfactant by saponification method.

8. Determination of Freundlich and Langmuir constants using activated charcoal.

9. Determination of critical micellar concentration of surfactants.

10. Determination of stability constant and donor acceptor ratio of PABACaffeine complex by solubility method.

11. Determination of stability constant and donor acceptor ratio of Cupric-Glycine complex by pH titration method.